Endocrine Abstracts

Introduction: Diabetic neuropathy is the most common cause of neuropathy worldwide and is known to affect approximately half of all diabetic patients. It significantly impairs the quality of life of patients.Aim of the study: To establish the predictive factors of distal symmetric polyneuropathy (DSPN) in diabetic patients.Methods: This is a descriptive cross-sectional study including 116 patients. The diagnosis of PNDS was establi...

Introduction: The prevalence of diabetes in the world population is increasing day by day so that its frequency reaches epidemic proportions. As a result, the complications of diabetes are becoming more and more frequent. Diabetic neuropathy, the most common complication which affect up to half of the patients.Purpose of the study: To establish the prevalence of distal symmetrical polyneuropathy (DSPN) in diabetic patients and demonstrate the importance ...

Objective: to analyze the dietary and metabolic factors predictive of the occurrence of pancreatitis in patients with type 1 diabetes mellitus (T1DM).Patients and Methods: Analytical case-control study of 31 T1DM patients separated into two subgroups: G1 (n=10): T1DM cases with pancreatitis. G2 (n=21): T1DM controls without pancreatitis.Results: The age at diagnosis of T1DM was comparable between the two groups. A...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth, cardiometabolic disturbances and an increased neoplastic risk. This study aims to assess the tumorigenic potential of GH excessive secretion.Patients and Methods: We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker...

Background and aim: Acromegaly is a rare condition caused by an excessive secretion of growth hormone (GH) and insulin-like growth factor1 (IGF-1), which are responsible for exaggerated somatic growth and cardiometabolic disturbances. This study aims to determine the prevalence of obesity in patients with acromegalyPatients and Methods : We conducted a retrospective study (1997-2020) at the Endocrinology department of Hedi Chaker University Hospital, Sfa...

IntroductionThe association of type 1 diabetes with other autoimmune diseases is well known due to a common genetic terrain of varied clinical expressions. However, the occurrence of systemic diseases in diabetic patient, whatever the type of diabetes, is poorly studied. The objective of this study is to describe autoimmune and inflammatory diseases associated with diabetes.Materials and methodsIt ’ s a ...

Introduction: Congenital adrenal hyperplasia (CAH) in its classical form is an early-onset and challenging-to-treat condition with long-term evolution associated with significant morbidity, typically involving metabolism, bone, and gonadal aspects. Through this specific case study, we illustrate one of the rare complications of CAH in adulthood.Case Report: A 24-year-old patient, born of consanguineous parents, has been monitored since birth for classica...

Introduction: Multiple Endocrine Neoplasia Type 1 (MEN1) represents a rare genetic disorder characterized by a predisposition to various endocrine neoplasms, primarily affecting the parathyroid, endocrine pancreas, and pituitary gland. So far, Papillary Thyroid Carcinoma (PTC) has been detected in more than 25% of individuals bearing the MEN mutation, even though this particular cancer type does not usually belong to the clinical spectrum associated with this condition.<p ...

Introduction: Acromegaly is a rare pathology characterized by chronic hypersecretion of Growth Hormone (GH) and Insulin-like Growth Factor-1 (IGF-1) that causes somatic, metabolic, and systemic changes. There are few data in the literature on the impact of the disease in male.Patients and methods: Retrospective descriptive study including 15 adult males with acromegaly hospitalized in the endocrinology department of the Hedi Chaker Sfax university hospit...

Introduction: Pheochromocytoma represents only 5% of adrenal incidentalomas. It is malignant in only 10% of cases. We report a case of pheochrompcytoma with suspucion of double cortico-meullary component or an ectopic secretion of CRH in the context of neurofibromatosis type1Observation: A26year old woman with a history of unilateral renal lithiasis, colic and breast neoplasia, with no notable personal history, consulted for right lumbar pain. An abdomin...